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Processing of complex N-glycans in IgG Fc-region is affected by core fucosylation
We investigated N-glycan processing of immunoglobulin G1 using the monoclonal antibody cetuximab (CxMab), which has a glycosite in the Fab domain in addition to the conserved Fc glycosylation, as a reporter. Three GlcNAc (Gn) terminating bi-antennary glycoforms of CxMab differing in core fucosylatio...
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| Pubblicato in: | MAbs |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622071/ https://ncbi.nlm.nih.gov/pubmed/26067753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1053683 |
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