In Planta Glycan Engineering and Functional Activities of IgE Antibodies

Human immunoglobulin E (IgE) is the most extensively glycosylated antibody isotype so glycans attached to the seven N-glycosites (NGS) in its Fab and Fc domains may modulate its functions. However, targeted modification of glycans in multiply glycosylated proteins remains a challenge. Here, we appli...

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Bibliographic Details
Published in:Front Bioeng Biotechnol
Main Authors: Montero-Morales, Laura, Maresch, Daniel, Crescioli, Silvia, Castilho, Alexandra, Ilieva, Kristina M., Mele, Silvia, Karagiannis, Sophia N., Altmann, Friedrich, Steinkellner, Herta
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Bioengineering and Biotechnology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781838/
https://ncbi.nlm.nih.gov/pubmed/31632959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00242
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