Expression Profiling and Glycan Engineering of IgG Subclass 1–4 in Nicotiana benthamiana

IgG, the main serum immunoglobulin isotype, exists in four subclasses which selectively appear with distinctive glycosylation profiles. However, very little is known about the biological consequences mainly due to the difficulties in the generation of distinct IgG subtypes with targeted glycosylatio...

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Библиографические подробности
Опубликовано в: :Front Bioeng Biotechnol
Главные авторы: Kallolimath, Somanath, Hackl, Thomas, Gahn, Raphaela, Grünwald-Gruber, Clemens, Zich, Wilhelm, Kogelmann, Benjamin, Lux, Anja, Nimmerjahn, Falk, Steinkellner, Herta
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Bioengineering and Biotechnology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7393800/
https://ncbi.nlm.nih.gov/pubmed/32793574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2020.00825
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