Proteolytic and N-Glycan Processing of Human α1-Antitrypsin Expressed in Nicotiana benthamiana

Plants are increasingly being used as an expression system for complex recombinant proteins. However, our limited knowledge of the intrinsic factors that act along the secretory pathway, which may compromise product integrity, renders process design difficult in some cases. Here, we pursued the reco...

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Bibliographic Details
Published in:Plant Physiol
Main Authors: Castilho, Alexandra, Windwarder, Markus, Gattinger, Pia, Mach, Lukas, Strasser, Richard, Altmann, Friedrich, Steinkellner, Herta
Format: Artigo
Language:Inglês
Published: American Society of Plant Biologists 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256845/
https://ncbi.nlm.nih.gov/pubmed/25355867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.114.250720
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