Transient pentameric IgM fulfill biological function—Effect of expression host and transfection on IgM properties

Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we present transient expression of IgM antibodies (IgM61...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Hennicke, Julia, Schwaigerlehner, Linda, Grünwald-Gruber, Clemens, Bally, Isabelle, Ling, Wai Li, Thielens, Nicole, Reiser, Jean-Baptiste, Kunert, Renate
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067452/
https://ncbi.nlm.nih.gov/pubmed/32163462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229992
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