Transient pentameric IgM fulfill biological function—Effect of expression host and transfection on IgM properties

Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we present transient expression of IgM antibodies (IgM61...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Hennicke, Julia, Schwaigerlehner, Linda, Grünwald-Gruber, Clemens, Bally, Isabelle, Ling, Wai Li, Thielens, Nicole, Reiser, Jean-Baptiste, Kunert, Renate
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067452/
https://ncbi.nlm.nih.gov/pubmed/32163462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229992
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