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Targeting cell surface β(2)-microglobulin by pentameric IgM antibodies
Monoclonal antibodies (mAbs) specific for human β(2)-microglobulin (β(2)M) have been shown to induce tumour cell apoptosis in haematological and solid tumours via recruiting major histocompatibility complex (MHC) class I molecules into and excluding cytokine receptors from the lipid rafts. Based on...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111817/ https://ncbi.nlm.nih.gov/pubmed/21554263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2011.08714.x |
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