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Analysis of the interaction of monoclonal antibodies with surface IgM on neoplastic B-cells

In vitro studies identified three Burkitts lymphoma cell lines, Ramos, MUTU-I and Daudi, that were growth inhibited by anti-IgM antibody. However, only Ramos and MUTU-I were sensitive to monoclonal antibodies (mAb) recognizing the Fc region of surface IgM (anti-Fcμ). Experiments using anti-Fcμ mAb (...

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Detalhes bibliográficos
Main Authors: Cragg, M S, Zhang, L, French, R R, Glennie, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2362654/
https://ncbi.nlm.nih.gov/pubmed/10070880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6690136
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