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Human-like mouse models for testing the efficacy and safety of anti-β(2)-microglobulin monoclonal antibodies to treat myeloma
PURPOSE: We recently demonstrated that anti-β(2)-microglobulin (β(2)M) mAbs have remarkably strong apoptotic effects on myeloma cells in vitro and in SCID(-hu) mice. However, whether the mAbs will be therapeutic and safe in the treatment of myeloma patients, in whom every tissues express low densiti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659684/ https://ncbi.nlm.nih.gov/pubmed/19188166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1823 |
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