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Anti-β(2)M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity

Our previous studies showed that anti-β(2)M monoclonal antibodies (mAbs) at high doses have direct apoptotic effects on myeloma cells, suggesting that anti-β(2)M mAbs might be developed as a novel therapeutic agent. In this study, we investigated the ability of the mAbs at much lower concentrations...

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Vydáno v:Int J Cancer
Hlavní autoři: Zhang, Mingjun, Qian, Jianfei, Lan, Yongsheng, Lu, Yong, Li, Haiyan, Hong, Bangxing, Zheng, Yuhuan, He, Jin, Yang, Jing, Yi, Qing
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230340/
https://ncbi.nlm.nih.gov/pubmed/24474467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28745
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