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Transient pentameric IgM fulfill biological function—Effect of expression host and transfection on IgM properties

Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we present transient expression of IgM antibodies (IgM61...

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Publicat a:PLoS One
Autors principals: Hennicke, Julia, Schwaigerlehner, Linda, Grünwald-Gruber, Clemens, Bally, Isabelle, Ling, Wai Li, Thielens, Nicole, Reiser, Jean-Baptiste, Kunert, Renate
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067452/
https://ncbi.nlm.nih.gov/pubmed/32163462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229992
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