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Recognition of Cytosolic DNA by cGAS and other STING-dependent sensors
The presence of DNA in the cytoplasm of mammalian cells is perceived as a danger signal, alerting the host to the presence of microbial infection. In response to the detection of cytoplasmic DNA, the immune system mounts a programmed response that involves the transcription of anti-viral genes such...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621431/ https://ncbi.nlm.nih.gov/pubmed/24356864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201344127 |
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