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Engagement of CD153 (CD30 Ligand) by CD30(+) T Cells Inhibits Class Switch DNA Recombination and Antibody Production in Human IgD(+) IgM(+) B Cells()
CD153 (CD30 ligand) is a member of the TNF ligand/cytokine family expressed on the surface of human B cells. Upon exposure to IL-4, a critical Ig class switch-inducing cytokine, Ag-activated T cells express CD30, the CD153 receptor. The observation that dysregulated IgG, IgA, and/or IgE production i...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621014/ https://ncbi.nlm.nih.gov/pubmed/10878352 |
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