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Association of activated Gα(q) to the tumor suppressor Fhit is enhanced by phospholipase Cβ

BACKGROUND: G proteins are known to modulate various growth signals and are implicated in the regulation of tumorigenesis. The tumor suppressor Fhit is a newly identified interaction partner of G(q) proteins that typically stimulate the phospholipase C pathway. Activated Gα(q) subunits have been sho...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Zuo, Hao, Wong, Yung H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619496/
https://ncbi.nlm.nih.gov/pubmed/26497576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1802-z
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