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An intact helical domain is required for Gα(14) to stimulate phospholipase Cβ
BACKGROUND: Stimulation of phospholipase Cβ (PLCβ) by the activated α-subunit of G(q) (Gα(q)) constitutes a major signaling pathway for cellular regulation, and structural studies have recently revealed the molecular interactions between PLCβ and Gα(q). Yet, most of the PLCβ-interacting residues ide...
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| Publicado no: | BMC Struct Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573470/ https://ncbi.nlm.nih.gov/pubmed/26377666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-015-0043-3 |
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