Self-masking in an intact ERM-merlin protein: an active role for the central α-helical domain

Ezrin/Radixin/moesin (ERM) family members provide a regulated link between the cortical actin cytoskeleton and the plasma membrane to govern membrane structure and organization. Here we report the crystal structure of intact insect moesin, revealing that its essential yet previously uncharacterized...

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Hlavní autoři: Li, Qianzhi, Nance, Mark R., Kulikauskas, Rima, Nyberg, Kevin, Fehon, Richard, Karplus, P. Andrew, Bretscher, Anthony, Tesmer, John J. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1796844/
https://ncbi.nlm.nih.gov/pubmed/17134719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.075
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