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Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase

Merlin and Moesin are closely related members of the 4.1 Ezrin/Radixin/Moesin domain superfamily implicated in regulating proliferation and epithelial integrity, respectively. The activity of both proteins is regulated by head to tail folding that is controlled, in part, by phosphorylation. Few upst...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hughes, Sarah C., Fehon, Richard G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064571/
https://ncbi.nlm.nih.gov/pubmed/17060498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608009
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