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Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are coordinately regulated by the Slik kinase

Merlin and Moesin are closely related members of the 4.1 Ezrin/Radixin/Moesin domain superfamily implicated in regulating proliferation and epithelial integrity, respectively. The activity of both proteins is regulated by head to tail folding that is controlled, in part, by phosphorylation. Few upst...

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Autori principali: Hughes, Sarah C., Fehon, Richard G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064571/
https://ncbi.nlm.nih.gov/pubmed/17060498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608009
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