C/EBPα Activates Pre-existing and De Novo Macrophage Enhancers during Induced Pre-B Cell Transdifferentiation and Myelopoiesis

Transcription-factor-induced somatic cell conversions are highly relevant for both basic and clinical research yet their mechanism is not fully understood and it is unclear whether they reflect normal differentiation processes. Here we show that during pre-B-cell-to-macrophage transdifferentiation,...

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Pubblicato in:Stem Cell Reports
Autori principali: van Oevelen, Chris, Collombet, Samuel, Vicent, Guillermo, Hoogenkamp, Maarten, Lepoivre, Cyrille, Badeaux, Aimee, Bussmann, Lars, Sardina, Jose Luis, Thieffry, Denis, Beato, Miguel, Shi, Yang, Bonifer, Constanze, Graf, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618662/
https://ncbi.nlm.nih.gov/pubmed/26235892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.06.007
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