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CCAAT/enhancer binding protein α (C/EBPα)-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation

Earlier work has shown that pre-B cells can be converted into macrophages by the transcription factor CCAAT/enhancer binding protein α at very high frequencies. Using this system, we performed a systematic analysis of whether during transdifferentiation the cells transiently reactivate progenitor-re...

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Detalhes bibliográficos
Main Authors: Di Tullio, Alessandro, Manh, Thien Phong Vu, Schubert, Alexis, Castellano, Giancarlo, Månsson, Robert, Graf, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193237/
https://ncbi.nlm.nih.gov/pubmed/21969581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112169108
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