Logical modeling of lymphoid and myeloid cell specification and transdifferentiation

Blood cells are derived from a common set of hematopoietic stem cells, which differentiate into more specific progenitors of the myeloid and lymphoid lineages, ultimately leading to differentiated cells. This developmental process is controlled by a complex regulatory network involving cytokines and...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Collombet, Samuel, van Oevelen, Chris, Sardina Ortega, Jose Luis, Abou-Jaoudé, Wassim, Di Stefano, Bruno, Thomas-Chollier, Morgane, Graf, Thomas, Thieffry, Denis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
Onderwerpen:
Sackler Colloquium on Gene Regulatory Networks and Network Models in Development and Evolution
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468615/
https://ncbi.nlm.nih.gov/pubmed/28584084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610622114
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