Overexpression of the Mitotic Checkpoint Genes BUB1 and BUBR1 is Associated with Genomic Complexity in Clear Cell Kidney Carcinomas

Background: A defective mitotic checkpoint has been proposed to contribute to chromosomal instability (CIN). We have previously shown that expression changes of the mitotic arrest deficiency (MAD) gene family plays a role in renal cell cancer (RCC) characterized by numerical chromosomal changes, nam...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Pinto, Mafalda, Vieira, Joana, Ribeiro, Franclim R., Soares, Maria J., Henrique, Rui, Oliveira, Jorge, Jerónimo, Carmen, Teixeira, Manuel R.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618595/
https://ncbi.nlm.nih.gov/pubmed/18791270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2008-0439
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