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Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation

Aberrant constitutive activation of receptor-mediated downstream signalling plays an active role in the deregulation of cell cycle control. The mitotic spindle checkpoint is important in preventing abnormal mitotic cell cycle with chromosome missegregation from achieving neoplastic aneuploidy. Howev...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Jihyun, Park, Hye-Young, Kim, Suhyeon, Kim, Hyun-Soo, Park, Ji Y., Go, Heounjeong, Lee, Chang-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458268/
https://ncbi.nlm.nih.gov/pubmed/28410192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16762
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