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Pellino 1 inactivates mitotic spindle checkpoint by targeting BubR1 for ubiquitinational degradation
Aberrant constitutive activation of receptor-mediated downstream signalling plays an active role in the deregulation of cell cycle control. The mitotic spindle checkpoint is important in preventing abnormal mitotic cell cycle with chromosome missegregation from achieving neoplastic aneuploidy. Howev...
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| Опубликовано в: : | Oncotarget |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Impact Journals LLC
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458268/ https://ncbi.nlm.nih.gov/pubmed/28410192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16762 |
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