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Overexpression of Fbxo6 inactivates spindle checkpoint by interacting with Mad2 and BubR1
The spindle assembly checkpoint prevents chromosome mis-segregation during mitosis by delaying sister chromatid separation. Several F-box protein members play critical roles in maintaining genome stability and regulating cell cycle progress via ubiquitin-mediated protein degradation. Here, we showed...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6343701/ https://ncbi.nlm.nih.gov/pubmed/30526252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1557488 |
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