Attempts to restore scrapie prion infectivity after exposure to protein denaturants.

A wealth of experimental evidence argues that infectious prions are composed largely, if not entirely, of the scrapie isoform of the prion protein. We attempted to restore scrapie infectivity after exposure to protein denaturants including urea, chaotropic salts, and SDS. None of the procedures rest...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Prusiner, S B, Groth, D, Serban, A, Stahl, N, Gabizon, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC46182/
https://ncbi.nlm.nih.gov/pubmed/8464892
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