Chargement en cours...
Toward optimization of AgoshRNA moleculesthat use a non-canonical RNAi pathway: Variations in the top and bottom base pairs
Short hairpin RNAs (shRNAs) are widely used for gene knockdown by inducing the RNA interference (RNAi) mechanism. The shRNA precursor is processed by Dicer into small interfering RNAs (siRNAs) and subsequently programs the RNAi-induced silencing complex (RISC) to find a complementary target mRNA (mR...
Enregistré dans:
| Publié dans: | RNA Biol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615845/ https://ncbi.nlm.nih.gov/pubmed/25747107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1022024 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|