Comparison of Functional Variants in IFNL4 and IFNL3 for Association with Hepatitis C Virus Clearance

BACKGROUND & AIMS: Genetic polymorphisms within the interferon lambda (IFN-λ) region are strongly associated with hepatitis C virus (HCV) clearance; the IFNL4-ΔG/TT (rs368234815) polymorphism, which controls generation of the IFN-λ4 protein, is more strongly associated with HCV clearance than rs...

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Bibliografiset tiedot
Julkaisussa:J Hepatol
Päätekijät: O’Brien, Thomas R., Pfeiffer, Ruth M., Paquin, Ashley, Lang Kuhs, Krystle A., Chen, Sabrina, Bonkovsky, Herbert L., Edlin, Brian R., Howell, Charles D., Kirk, Gregory D., Kuniholm, Mark H., Morgan, Timothy R., Strickler, Howard D., Thomas, David L., Prokunina-Olsson, Ludmila
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615534/
https://ncbi.nlm.nih.gov/pubmed/26186989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.06.035
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