Association of the IFNL4-ΔG Allele With Impaired Spontaneous Clearance of Hepatitis C Virus

Interferon lambda 4 protein can be generated in IFNL4-ΔG carriers but not IFNL4-TT homozygotes. We studied 890 anti–hepatitis C virus (HCV)–positive participants in the Women's Interagency HIV Study. Among blacks (n = 555), HCV was more often cleared for those with genotype IFNL4-TT/TT (32.6%;...

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Библиографические подробности
Главные авторы: Aka, Peter V., Kuniholm, Mark H., Pfeiffer, Ruth M., Wang, Alan S., Tang, Wei, Chen, Sabrina, Astemborski, Jacquie, Plankey, Michael, Villacres, Maria C., Peters, Marion G., Desai, Seema, Seaberg, Eric C., Edlin, Brian R., Strickler, Howard D., Thomas, David L., Prokunina-Olsson, Ludmila, Sharp, Gerald B., O'Brien, Thomas R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2014
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883162/
https://ncbi.nlm.nih.gov/pubmed/23956438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit433
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