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Comparison of Functional Variants in IFNL4 and IFNL3 for Association with Hepatitis C Virus Clearance

BACKGROUND & AIMS: Genetic polymorphisms within the interferon lambda (IFN-λ) region are strongly associated with hepatitis C virus (HCV) clearance; the IFNL4-ΔG/TT (rs368234815) polymorphism, which controls generation of the IFN-λ4 protein, is more strongly associated with HCV clearance than rs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Hepatol
Egile Nagusiak: O’Brien, Thomas R., Pfeiffer, Ruth M., Paquin, Ashley, Lang Kuhs, Krystle A., Chen, Sabrina, Bonkovsky, Herbert L., Edlin, Brian R., Howell, Charles D., Kirk, Gregory D., Kuniholm, Mark H., Morgan, Timothy R., Strickler, Howard D., Thomas, David L., Prokunina-Olsson, Ludmila
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615534/
https://ncbi.nlm.nih.gov/pubmed/26186989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.06.035
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