Llwytho...

PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD)

Abnormal protein interactions of mutant huntingtin (Htt) triggered by polyglutamine expansion are thought to mediate Huntington's disease (HD) pathogenesis. Here, we explored a functional interaction of Htt with protein arginine methyltransferase 5 (PRMT5), an enzyme mediating symmetrical dimet...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Cycle
Prif Awduron: Ratovitski, Tamara, Arbez, Nicolas, Stewart, Jacqueline C, Chighladze, Ekaterine, Ross, Christopher A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615115/
https://ncbi.nlm.nih.gov/pubmed/25927346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1033595
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