Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo

Recently, we reported that saturated and unsaturated fatty acids trigger autophagy through distinct signal transduction pathways. Saturated fatty acids like palmitate (PA) induce autophagic responses that rely on phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3, best known as VPS34) a...

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Publicat a:Cell Cycle
Autors principals: Enot, David P., Niso-Santano, Mireia, Durand, Sylvère, Chery, Alexis, Pietrocola, Federico, Vacchelli, Erika, Madeo, Frank, Galluzzi, Lorenzo, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615103/
https://ncbi.nlm.nih.gov/pubmed/26098646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1064206
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