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Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo

Recently, we reported that saturated and unsaturated fatty acids trigger autophagy through distinct signal transduction pathways. Saturated fatty acids like palmitate (PA) induce autophagic responses that rely on phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3, best known as VPS34) a...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Enot, David P., Niso-Santano, Mireia, Durand, Sylvère, Chery, Alexis, Pietrocola, Federico, Vacchelli, Erika, Madeo, Frank, Galluzzi, Lorenzo, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615103/
https://ncbi.nlm.nih.gov/pubmed/26098646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1064206
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