α-Ketoglutarate inhibits autophagy

The metabolite α-ketoglutarate is membrane-impermeable, meaning that it is usually added to cells in the form of esters such as dimethyl −ketoglutarate (DMKG), trifluoromethylbenzyl α-ketoglutarate (TFMKG) and octyl α-ketoglutarate (O-KG). Once these compounds cross the plasma membrane, they are hyd...

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Bibliografische gegevens
Gepubliceerd in:Aging (Albany NY)
Hoofdauteurs: Baracco, Elisa Elena, Castoldi, Francesca, Durand, Sylvère, Enot, David P., Tadic, Jelena, Kainz, Katharina, Madeo, Frank, Chery, Alexis, Izzo, Valentina, Maiuri, Maria Chiara, Pietrocola, Federico, Kroemer, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals 2019
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Priority Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594794/
https://ncbi.nlm.nih.gov/pubmed/31173576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102001
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