Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy

It has been a longstanding problem to identify specific and efficient pharmacological modulators of autophagy. Recently, we found that depletion of acetyl-coenzyme A (AcCoA) induced autophagic flux, while manipulations designed to increase cytosolic AcCoA efficiently inhibited autophagy. Thus, the c...

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Detaylı Bibliyografya
Yayımlandı:Autophagy
Asıl Yazarlar: Mariño, Guillermo, Pietrocola, Federico, Kong, Yongli, Eisenberg, Tobias, Hill, Joseph A, Madeo, Frank, Kroemer, Guido
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Autophagic Punctum
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119061/
https://ncbi.nlm.nih.gov/pubmed/24675140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28235
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