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Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers

Nutrient depletion, which is one of the physiological triggers of autophagy, results in the depletion of intracellular acetyl coenzyme A (AcCoA) coupled to the deacetylation of cellular proteins. We surmise that there are 3 possibilities to mimic these effects, namely (i) the depletion of cytosolic...

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Publicat a:Autophagy
Autors principals: Mariño, Guillermo, Pietrocola, Federico, Madeo, Frank, Kroemer, Guido
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502795/
https://ncbi.nlm.nih.gov/pubmed/25484097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.36413
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