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Caloric restriction promotes the stemness and antitumor activity of T lymphocytes

Recent findings have shed new light on the mechanisms through which tumor-infiltrating lymphocytes (TILs) maintain their cytotoxic potential in the context of checkpoint blockade or adoptive transfer therapies. As a consequence of the ionic unbalance occurring in the tumor microenvironment, TILs ent...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Pietrocola, Federico, Kroemer, Guido
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791451/
https://ncbi.nlm.nih.gov/pubmed/31646069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1616153
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