Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo

Recently, we reported that saturated and unsaturated fatty acids trigger autophagy through distinct signal transduction pathways. Saturated fatty acids like palmitate (PA) induce autophagic responses that rely on phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3, best known as VPS34) a...

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Vydáno v:Cell Cycle
Hlavní autoři: Enot, David P., Niso-Santano, Mireia, Durand, Sylvère, Chery, Alexis, Pietrocola, Federico, Vacchelli, Erika, Madeo, Frank, Galluzzi, Lorenzo, Kroemer, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615103/
https://ncbi.nlm.nih.gov/pubmed/26098646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1064206
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