The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene

Pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI) are heritable ectopic mineralization disorders. Most cases of PXE and many cases of GACI harbor mutations in the ABCC6 gene. There is no effective treatment for these disorders. We explored the potential efficacy...

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Bibliografske podrobnosti
izdano v:Cell Cycle
Main Authors: Li, Qiaoli, Sundberg, John P, Levine, Michael A, Terry, Sharon F, Uitto, Jouni
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615006/
https://ncbi.nlm.nih.gov/pubmed/25607347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1007809
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