The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene

Pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI) are heritable ectopic mineralization disorders. Most cases of PXE and many cases of GACI harbor mutations in the ABCC6 gene. There is no effective treatment for these disorders. We explored the potential efficacy...

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Publicat a:Cell Cycle
Autors principals: Li, Qiaoli, Sundberg, John P, Levine, Michael A, Terry, Sharon F, Uitto, Jouni
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615006/
https://ncbi.nlm.nih.gov/pubmed/25607347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1007809
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