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Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy
Generalized arterial calcification of infancy (GACI) is an intractable ectopic mineralization disorder caused by mutations in the ENPP1 gene resulting in reduced plasma inorganic pyrophosphate levels. We previously characterized the Enpp1(asj) mutant mouse as a model of GACI, and we have now explore...
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| Publicado no: | J Invest Dermatol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731049/ https://ncbi.nlm.nih.gov/pubmed/26763447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.377 |
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