Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy

Generalized arterial calcification of infancy (GACI) is an intractable ectopic mineralization disorder caused by mutations in the ENPP1 gene resulting in reduced plasma inorganic pyrophosphate levels. We previously characterized the Enpp1(asj) mutant mouse as a model of GACI, and we have now explore...

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Detalles Bibliográficos
Publicado en:J Invest Dermatol
Autores principales: Li, Qiaoli, Kingman, Joshua, Sundberg, John P., Levine, Michael A., Uitto, Jouni
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731049/
https://ncbi.nlm.nih.gov/pubmed/26763447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.377
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