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Dual Effects of Bisphosphonates on Ectopic Skin and Vascular Soft Tissue Mineralization versus Bone Microarchitecture in a Mouse Model of Generalized Arterial Calcification of Infancy

Generalized arterial calcification of infancy (GACI) is an intractable ectopic mineralization disorder caused by mutations in the ENPP1 gene resulting in reduced plasma inorganic pyrophosphate levels. We previously characterized the Enpp1(asj) mutant mouse as a model of GACI, and we have now explore...

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書誌詳細
出版年:J Invest Dermatol
主要な著者: Li, Qiaoli, Kingman, Joshua, Sundberg, John P., Levine, Michael A., Uitto, Jouni
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731049/
https://ncbi.nlm.nih.gov/pubmed/26763447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/JID.2015.377
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