The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene

Pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI) are heritable ectopic mineralization disorders. Most cases of PXE and many cases of GACI harbor mutations in the ABCC6 gene. There is no effective treatment for these disorders. We explored the potential efficacy...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Li, Qiaoli, Sundberg, John P, Levine, Michael A, Terry, Sharon F, Uitto, Jouni
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615006/
https://ncbi.nlm.nih.gov/pubmed/25607347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1007809
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