Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions

In inflammatory central nervous system conditions such as multiple sclerosis, breakdown of the blood–brain barrier is a key event in lesion pathogenesis, predisposing to oedema, excitotoxicity, and ingress of plasma proteins and inflammatory cells. Recently, we showed that reactive astrocytes drive...

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Vydáno v:Brain
Hlavní autoři: Chapouly, Candice, Tadesse Argaw, Azeb, Horng, Sam, Castro, Kamilah, Zhang, Jingya, Asp, Linnea, Loo, Hannah, Laitman, Benjamin M., Mariani, John N., Straus Farber, Rebecca, Zaslavsky, Elena, Nudelman, German, Raine, Cedric S., John, Gareth R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614128/
https://ncbi.nlm.nih.gov/pubmed/25805644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv077
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