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Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease
In inflammatory CNS conditions such as multiple sclerosis (MS), current options to treat clinical relapse are limited, and more selective agents are needed. Disruption of the blood-brain barrier (BBB) is an early feature of lesion formation that correlates with clinical exacerbation, leading to edem...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386814/ https://ncbi.nlm.nih.gov/pubmed/22653056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI60842 |
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