TGFβ1 induces Jagged1 expression in astrocytes via ALK5 and Smad3 and regulates the balance between oligodendrocyte progenitor proliferation and differentiation

Notch1 receptor signaling regulates oligodendrocyte progenitor differentiation and myelin formation in development, and during remyelination in the adult CNS. In active multiple sclerosis lesions, Notch1 localizes to oligodendrocyte lineage cells, and its ligand Jagged1 is expressed by reactive astr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Yueting, Zhang, Jingya, Navrazhina, Kristina, Argaw, Azeb Tadesse, Zameer, Andleeb, Gurfein, Blake T., Brosnan, Celia F., John, Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913704/
https://ncbi.nlm.nih.gov/pubmed/20169621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.20978
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados