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VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown
Breakdown of the blood-brain barrier (BBB) is an early and significant event in CNS inflammation. Astrocyte-derived VEGF-A has been implicated in this response, but the underlying mechanisms remain unresolved. Here, we identify the endothelial transmembrane tight junction proteins claudin-5 (CLN-5)...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2644149/ https://ncbi.nlm.nih.gov/pubmed/19174516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808698106 |
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