Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions

In inflammatory central nervous system conditions such as multiple sclerosis, breakdown of the blood–brain barrier is a key event in lesion pathogenesis, predisposing to oedema, excitotoxicity, and ingress of plasma proteins and inflammatory cells. Recently, we showed that reactive astrocytes drive...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Chapouly, Candice, Tadesse Argaw, Azeb, Horng, Sam, Castro, Kamilah, Zhang, Jingya, Asp, Linnea, Loo, Hannah, Laitman, Benjamin M., Mariani, John N., Straus Farber, Rebecca, Zaslavsky, Elena, Nudelman, German, Raine, Cedric S., John, Gareth R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614128/
https://ncbi.nlm.nih.gov/pubmed/25805644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv077
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