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Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing
Despite its function as an inhibitor of urokinase and tissue-type plasminogen activator (PA), PA inhibitor-1 (PAI-1) has a paradoxical pro-tumorigenic role in cancer promoting angiogenesis and tumor cell survival. In this review we summarize pre-clinical evidence in support of the pro-tumorigenic fu...
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| Publicado en: | Cancer Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613764/ https://ncbi.nlm.nih.gov/pubmed/26180080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0876 |
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