Insulin down-regulates the expression of ubiquitin E3 ligases partially by inhibiting the activity and expression of AMP-activated protein kinase in L6 myotubes

While insulin is an anabolic hormone, AMP-activated protein kinase (AMPK) is not only a key energy regulator, but it can also control substrate metabolism directly by inducing skeletal muscle protein degradation. The hypothesis of the present study was that insulin inhibits AMPK and thus down-regula...

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Detaylı Bibliyografya
Yayımlandı:Biosci Rep
Asıl Yazarlar: Deng, Hu-Ping, Chai, Jia-Ke, Shen, Chuan-An, Zhang, Xi-Bo, Ma, Li, Sun, Tian-Jun, Hu, Qing-Gang, Chi, Yun-Fei, Dong, Ning
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2015
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613693/
https://ncbi.nlm.nih.gov/pubmed/26193886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150017
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