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Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis
The COP9 signalosome subunit 6 (CSN6), which is involved in ubiquitin-mediated protein degradation, is overexpressed in many types of cancer. CSN6 is critical in causing p53 degradation and malignancy, but its target in cell cycle progression is not fully characterized. Constitutive photomorphogenic...
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| Publié dans: | Cell Cycle |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613181/ https://ncbi.nlm.nih.gov/pubmed/25945542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1046655 |
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