Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis

The COP9 signalosome subunit 6 (CSN6), which is involved in ubiquitin-mediated protein degradation, is overexpressed in many types of cancer. CSN6 is critical in causing p53 degradation and malignancy, but its target in cell cycle progression is not fully characterized. Constitutive photomorphogenic...

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Bibliografski detalji
Izdano u:Cell Cycle
Glavni autori: Choi, Hyun Ho, Guma, Sergei, Fang, Lekun, Phan, Liem, Ivan, Cristina, Baggerly, Keith, Sood, Anil, Lee, Mong-Hong
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613181/
https://ncbi.nlm.nih.gov/pubmed/25945542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1046655
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